The late David Lynch's Los Angeles home is on sale for $US15 million ($A23 million).

The Twin Peaks director, who died in January at the age of 78, used the Hollywood Hills compound as a base for much of his work, editing Mulholland Drive there, with one of its buildings featured prominently in his 1997 film Lost Highway.

The sale was reported by The Washington Post, which added the US director's family urged the buyer to preserve the property's unique cinematic and architectural legacy.

Marc Silver, listing agent with the Agency Beverly Hills, said demand had been overwhelming.

"Buyers have to be very well prequalified in order to actually have a showing at the property. The family's strong desire is that the next owner protects, preserves and honours what David created."

Lynch's com

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