SANTA CLARA, Calif. — The San Francisco 49ers have overcome injuries to star players to pull out three straight wins to open the season in games that weren't decided until the closing minutes.

The latest came when backup quarterback Mac Jones led a drive to set up Eddy Pineiro's 35-yard field goal on the final play of a 16-15 win over Arizona on Sunday.

As satisfying as the 3-0 start is, the Niners now might be facing their toughest challenge: Star defensive end Nick Bosa has a torn ACL in his right knee and will be out the rest of the season.

“You don’t just replace a guy like Nick,” coach Kyle Shanahan said Monday. “Everyone’s got to keep continuing to get better at everything. Same thing I’d be preaching if we did have Nick, too. When you lose your better players, it gets harder. ...

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