“There’s no downside” to avoiding Tylenol or acetaminophen use while pregnant.

President Donald Trump on Sept. 22, 2025, in a press conference

Obstetricians have long advised their pregnant patients that Tylenol is the safest option to reduce fever or pain. President Donald Trump stood before a national audience on Sept. 22 and contradicted that.

“Don’t take Tylenol,” Trump said during an hourlong White House press conference that included his leading health appointees. “There’s no downside. Don’t take it. You’ll be uncomfortable. It won’t be as easy, maybe, but don’t take it. If you’re pregnant, don’t take Tylenol.”

His advice has no clear basis in research and contradicts long-standing science and medical guidance. And there are downsides to avoiding acetaminophen, the active ingredi

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