Of the 49ers' early flurry of injuries to start the 2025 NFL season, star edge rusher Nick Bosa's ACL injury is perhaps the most impactful.

Not only is Bosa out for the season, but now San Francisco must rely on unproven players even more in an already-inexperienced defensive line group.

On Thursday morning, general manager John Lynch joined Brian Murphy and Markus Boucher on KNBR to discuss how the 49ers will move forward this year without the five-time Pro Bowl selection .

"First of all, my heart just goes out to him. He puts so much into it. There's not anybody in the league that puts more into the preparation," Lynch told Murphy and Boucher. "He lives for football and being the best player he can be. ...

"It's a crushing blow to our team, but that's what this sport is. You'r

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