COLUMBUS, Ohio (WCMH) -- A Columbus family is on a mission to find a cure for a rare genetic disorder and Saturday morning was their third annual Hope With Lo 5k.

“We believe that hope isn’t a feeling that it's a force. We’ve been so fortunate as we started this journey putting hope into action,” said Jake Kaufman, co-founder of Hope With Lo.

At the center of their efforts is their daughter Lola, also known as Lo. NBC4 first introduced you to them in 2023. Lo has Zellweger Spectrum Disorder. It affects her internal health as well as sight, hearing and development. There is currently no cure.

“We’re really thankful that Lo is doing as well as she is. When you get this diagnosis they pretty much tell you like we don’t know what to expect. Very few kiddos that have this diagnosis make it t

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