Is Joe Mixon out for the season? When is Joe Mixon coming back? The latest Joe Mixon injury update and fantasy football outlook heading into Week 5 of 2025.

Houston Texans running back Joe Mixon (foot) has remained on the non-football/injury reserve list since the beginning of the regular season. However, with his practice window opening this week, Mixon could be cleared to begin ramping up for his eventual return.

Despite this, the team has not provided many updates regarding his status, which has kept his status in doubt.

Will Mixon play again this season? Should fantasy managers stash him on their bench? Let's dive in! Be sure to check all of our fantasy football rankings for 2025:

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