The Week 5 NFL schedule kicks off with a 'Thursday Night Football' showdown between the San Francisco 49ers and Los Angeles Rams. Kickoff is scheduled for 8:15 p.m. ET at SoFi Stadium in Inglewood, Calif. Both teams feature a mix of proven star power and young talent. San Francisco's Christian McCaffrey and the Rams' Puka Nacua headline the NFL DFS player pool and can be rostered together in showdown DFS contests. Other players that will be popular NFL DFS picks include Mac Jones, Matthew Stafford, and Kyren Williams. Meanwhile potential NFL DFS values include Tutu Atwell, Demarcus Robinson and Marquez-Valdes Scantling.

How should they play into your NFL DFS strategy for 49ers vs. Rams, and which other daily Fantasy picks should be in your NFL DFS lineups? Before locking in any NFL DFS pi

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