St Kilda has overcome GWS by 14 points to jump inside the AFLW top eight for the first time since round one.
The Saints blew the match open with three unanswered goals in the third term, setting up the 4.6 (30) to 2.4 (16) win at Henson Park in Sydney.
But St Kilda will be sweating on scans to Nicola Barr, who came from the field with a suspected knee injury in the last quarter.
Darcy Guttridge and Bianca Jakobsson (ankle) also left the ground in the final term in a sour end to a successful road trip for the Saints.
Why Blues are a finals threat Photo shows Four Carlton AFLW players embrace as they celebrate a goal.
Carlton's emergence as a finals threat is no surprise, with the Blues now possessing the personnel to execute an effective game plan.
It was their fourth win in a row