Daijiworld Media Network - New Delhi

New Delhi, Oct 6: The 2025 Nobel Prize in Physiology or Medicine has been awarded to American scientists Mary E. Brunkow and Fred Ramsdell, along with Japanese immunologist Shimon Sakaguchi, for their pioneering work on how the immune system regulates itself to prevent attacking the body.

Announced by the Nobel Assembly at Karolinska Institutet, the laureates will equally share the prize money of 11 million Swedish kronor for uncovering the critical role of regulatory T cells, often described as the immune system’s “security guards.” These cells maintain peripheral immune tolerance, a vital mechanism that stops immune cells from launching attacks against the body’s own tissues.

Their groundbreaking discoveries have not only deepened scientific under

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