No. 22 Iowa State will look to shake off its first loss of the season when the Cyclones face Colorado in a Big 12 matinee Saturday in Boulder, Colo.

Colorado hopes to have coach Deion Sanders on the sideline. In his weekly press conference, Sanders said he will have a four-hour procedure and expects to be back at practice on Wednesday. Sanders said last week he was "hurting like crazy" and believed blood clots had returned to his leg.

"It's a long procedure," Sanders said Tuesday. "But I am having a procedure today, and prayerfully I'll be back at practice tomorrow. I don't plan on missing practice."

Cyclones coach Matt Campbell said a 38-30 loss at Cincinnati last week came down to a lack of execution in all three phases. Iowa State fell behind 31-7 before a second-half rally came up s

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