Matt's must-start fantasy football waiver wire defenses (D/ST) to stream and start for Week 6 of the 2025 season. His fantasy defense start 'em, sit 'em picks.

As we head into Week 6 of the 2025 fantasy football season, managers will continue to deal with byes, as well as injuries. Looking for a Week 6 D/ST streamer? We've got you covered! RotoBaller analyst Matt Donnelly drops his fantasy football must-start defenses (D/ST) for Week 6 of the 2025 season.

The fantasy football grind continues with impactful decisions coming on a weekly basis. We are here to help with your Week 6 D/ST streamers, to give you the tools needed to set those winning lineups and dominate your matchups.

Be sure to tune into RotoBaller Radio on SiriusXM (channel Sirius 210, XM 87) - every weekday morning at 6:0

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