Oct 5, 2025; Indianapolis, Indiana, USA; Las Vegas Raiders running back Ashton Jeanty (2) runs with the ball against the Indianapolis Colts during the second quarter at Lucas Oil Stadium. Mandatory Credit: Trevor Ruszkowski-Imagn Images

The NFL season so far has seen some younger running backs come out of the blue and make fantasy owners' rosters unlike ever before. The big names like Saquon, Henry, McCaffrey are doing their thing, but what about Bucky Irving, Cam Skattebo, Rico Dowdle, and De'Von Achane to name a few? The league is in great hands when it comes to ball carriers. Now, who should you Start/Sit during Week 6?

Start - Josh Jacobs, Green Bay Packers

Just like in this week's QB edition, where I "Start" Jordan Love against the Bengals, I felt the need to also throw Josh Jacobs in the mix due to how bad Cincinnati's defense really is. Jacobs is an old-school workhorse back who has a snap share percentage of over 80%. He is averaging just over 18 fantasy points a game as well.

Start - Cam Skattebo, New York Giants

Skattebo would apologize to Giants fans last week after the game. He is a fiesty individual, and I fully expect him to carry the load this week against the Eagles with something to really prove. Both carrying the ball and catching it. He could be a great substitute since the bye weeks have started around the NFL.

Start - Ashton Jeanty, Las Vegas Raiders

The Raiders will likely look to run the football frequently, given the struggles Geno Smith has faced under center this year. Jeanty is great after contact, and has picked up production within the last two weeks, rushing for over 200 yards after some considered him a "bust" for a week or two. It's a little early for that, folks!

Sit - Kenneth Gainwell, Pittsburgh Steelers

This is a terrible matchup for Gainwell, as they face a division opponent with Jaylen Warren reeling. The Browns are stout up front, and I expect this one to be a bit of a struggle scoring the football. It could, in fact, be a field goal game.

Sit - Alvin Kamara, New Orleans Saints

With how the Patriots held down James Cook of the Buffalo Bills last week? Kamara may not gain a single yard in this one if they play like that again! That's an exaggeration, but you get the point. I wouldn't do it this week!

Sit - TreVeyon Henderson, New England Patriots

On the flip side of that, it appears that I would not run the ball in this one. What I mean is the carries appear to belong to Patriots running back Rhamondre Stevenson once again for the time being. So trusting Henderson to get 20 carries in a time of need for your fantasy team may not be in this week's best interest.

This article originally appeared on Touchdown Wire: Fantasy Football Start 'Em, Sit 'Em Week 6: RB Edition

Reporting by Josh Petry, Touchdown Wire / Touchdown Wire

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