England captain Harry Kane is reportedly a 'major doubt' for with Wales at Wembley.
Kane has made an eye-catching start to the 2025-26 season with Bayern Munich, having netted 18 goals in 10 competitive appearances, including an effort in Saturday's 3-0 success against Eintracht Frankfurt.
However, he picked up a knock in the commanding victory, and was subsequently replaced by Chelsea loanee Nicolas Jackson in the 85th minute.
Kane was hopeful that he would be "fine" for international duty, but it has now emerged that he could miss Thursday's friendly.
Kane likely to miss Wales clash
According to Sky Sports News , Kane was unable to take part in Wednesday's training session due to the ankle issue, and instead, he worked on an individual programme indoors, along wi