Glee is one of the biggest shows in TV history.

The Ryan Murphy co-created series, which originally debuted on FOX , centers around New Directions, a high school glee club at the fictional William McKinley High School in Lima, Ohio, as they navigate the show choir circuit and the ups and downs of high school life.

The fan-favorite show got six Emmy Awards, four Golden Globes, and the SAG Award for its ensemble during its run, among many other notable recognitions and accolades.

Tragically, we lost several main actors from the series, as well as several beloved guest stars who made much buzzed-about cameos throughout the seasons.

We are remembering all of the cast members we’ve lost from the show over the years. Our thoughts are with everyone who has been affected by the loss

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