[This story contains spoilers from the season 22 premiere of Grey’s Anatomy, “Only the Strong Survive.”]

Grey’s Anatomy ended its 21st season with one of its biggest hospital explosions in recent memory when the operating floor of Grey Sloan Memorial Hospital went up in flames after a highly flammable acetylene tank was brought into the hospital. Only star Ellen Pompeo ‘s Meredith Grey and a handful of other doctors were shown after the blast — everyone else could have potentially been killed off when the hit show returned.

[This story contains spoilers from the season 22 premiere of Grey’s Anatomy, “Only the Strong Survive.”]

Grey’s Anatomy ended its 21st season with one of its biggest hospital explosions in recent memory when the operating floor of Grey Sloan Memorial Hospit

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