Ryan Reynolds thinks being a people-pleaser in Hollywood "doesn't work".

The 48-year-old actor made the claim during a John Candy: I Like Me event in Brooklyn, New York, where he recalled a "profound" musing he once heard from comedian Conan O'Brien.

Ryan explained: "He talks about people-pleasing and pleasers in Hollywood. And Bill Murray says it too. You just can't — it doesn't work.

"And what I found really fascinating about that is ... being a people-pleaser is, quite literally, antithetical to having a mental-health crisis or issue."

Asked to elaborate, Ryan replied: "As a people-pleaser, you don't want to burden anyone with your anything."

Ryan acknowledged that it's tough for people-pleasers to survive and thrive in the movie business.

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