The Week 6 NFL schedule features a compelling slate of matchups across the league, highlighted by several key games that could help shape the NFL playoff picture. The Denver Broncos (-7.5, 43.5), fresh off their 21-17 win over the defending Super Bowl champion Eagles, head to London to take on the Jets, the Pittsburgh Steelers (-5.5, 38.5) host the Browns in the only Sunday divisional contest, and the Tampa Bay Buccaneers (-3, 47.5) host the 49ers in a matchup of teams that are 3-2 against the spread. The Sunday slate wraps up with the Detroit Lions taking on the Kansas City Chiefs (-2.5, 52.5) in a potential Super Bowl preview. Lastly, 'Monday Night Football' features a two-game slate with Bills (-4.5, 50) vs. Falcons and Bears vs. Commanders (-4.5, 49.5).

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