By WILL WEISSERT, Associated Press

WASHINGTON (AP) — AstraZeneca on Friday became the second major pharmaceutical manufacturer to announce it had agreed to lower the cost of prescription drugs for Medicaid under a deal struck with the Trump administration that avoided its threats of steep tariffs.

President Donald Trump made the announcement in the Oval Office with AstraZeneca CEO Pascal Soriot, who said that during tough negotiations to reach a deal, Trump and his team of officials had “really kept me up at night.”

Under the agreement, AstraZeneca will charge most-favored-nation pricing to Medicaid, while guaranteeing such pricing on newly launched drugs, Trump said. That involves matching the lowest price offered in other developed nations.

“For many years, Americans have paid th

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