The San Francisco 49ers are preparing for one of their most critical primetime matchups of the 2025 season as they host the Atlanta Falcons on Sunday Night Football in Week 7. At 4-2 and sharing the top spot in the NFC West with the Seattle Seahawks, the 49ers find themselves at a crossroads. After a disappointing 30-19 road loss to the Tampa Bay Buccaneers in Week 6, San Francisco desperately needs to bounce back at Levi's Stadium against a Falcons defense that currently ranks first in several key defensive metrics. With quarterback Brock Purdy still questionable due to turf toe and backup Mac Jones dealing with his own injuries, the 49ers will need their most reliable weapon to deliver a signature performance.

That X-factor is none other than running back Christian McCaffrey .

CM

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