Stocks making big moves midday: ORCL ASTS, RVMD

Check out the companies making the biggest moves midday: AppFolio — The cloud-based business software provider climbed 7% after an upgrade to overweight from equal weight at KeyBanc, with a 12-month price target of $285, according to FactSet's StreetAccount service. AST SpaceMobile — Shares in the space-based broadband cellular network dropped 6% after more than doubling in the past month. Barclays double downgraded its investment rating to underweight from overweight while leaving its price target at $60, StreetAccount said. Revolution Medicines — The late-stage clinical oncology company jumped 10% after saying the Food and Drug Administration granted a voucher for daraxonrasib (RMC-6236), a multi-selective inhibitor, under the National Priority Voucher pilot program. Daraxonrasib is aime