Grey's Anatomy season 22, episode 2, "We Built This City", reveals Amelia's decision to temporarily leave the hospital, and there's actually a behind-the-scenes reason why. As with most of Shonda Rhimes' projects, ABC's premier medical drama is known for many plot twists. Over the years, Grey's Anatomy has pulled off unexpected deaths, including Derek and George's.
The Grey's Anatomy season 21 finale ended with a major cliffhanger that put some people's lives at risk. Immediately, questions of who might have died in the hospital explosion made the rounds, with Link being the most at risk. In the end, while Jo's husband survives, another one didn't — Natalie.
In hindsight, the situation was lose-lose for Amelia. She loves Link, although no longer romantically. Meanwhile, she ha