Key Takeaways
Nearly 70% of patients with treatment-resistant focal epilepsy saw their seizure frequency decrease over time
This challenges the belief that patients who fail to respond to multiple drugs have little chance for relief
It may take longer than previously thought for anti-seizure drugs to show a benefit, the study suggests
WEDNESDAY, Oct. 22, 2025 (HealthDay News) — For the estimated one-third of people with focal epilepsy who don’t respond well to initial medications, new research offers significant reason for optimism.
A study suggests that even those considered "treatment-resistant" may eventually see a substantial reduction in their seizures over time.
Focal epilepsy , the most common form of the neurological disorder, occurs when nerve cells in one area of the brain

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