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Younger Democratic candidates are challenging older incumbents amid increasing frustration over the party’s ineffective resistance to President Trump.

Recent challenges in San Francisco to Rep. Nancy Pelosi, long a party leader, have highlighted the trend.

SAN FRANCISCO — State Sen. Scott Wiener couldn’t wait any longer. The once-in-a-generation political opening he’d eyed for years had arrived, he decided — whether the grand dame of San Francisco politics agreed or not.

On Wednesday, Wiener, 55, a prolific and ambitious lawmaker, formally announced his candidacy for the San Francisco congressional seat held for nearly four decades by Rep. Nancy Pelosi, 85, who remains one of th

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