Millions of people worldwide take antidepressants. While these drugs can be very effective in treating mental health conditions such as depression and anxiety, they can also cause a range of physical side-effects – including weight gain, heart rate changes and altered blood pressure.

But not all antidepressants are equal when it comes to the physical effects they can have on the body, a new analysis published by myself and my colleagues has revealed.

We found clear and meaningful differences between the drugs, with some causing greater effects on weight, heart rate, cholesterol levels and blood pressure. For the millions of people who take these prescription drugs, these differences matter.

Our study brought together 151 randomised trials which contained data on 58,534 people an

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