Researchers from the Germans Trias i Pujol Research Institute and Hospital have reviewed the current knowledge on the use of tear-derived extracellular vesicles as a source of biomarkers for both ocular and neurodegenerative diseases . In their work, published in Extracellular Vesicles and Circulating Nucleic Acids, they highlight the advantages of this approach compared with more invasive methods and discuss the remaining challenges for its clinical application.
Ocular fluids provide a window into the health of the eye and the development of various pathologies. However, their study usually involves invasive techniques. "A wide range of eye diseases are being investigated, but the methods for obtaining aqueous humour and vitreous humour, the fluids inside the eye, are highly invasive