The San Francisco 49ers continue to battle key injuries, but they just keep winning as they enter Week 8 with a 5-2 record. Brock Purdy's toe injury has kept him out of all but two games this year, and Mac Jones is 4-1 as a starter and will be under center again on Sunday. The Houston Texans are just 2-4 on the year and have struggled offensively. That unit will be tested even more on Sunday as star receiver Nico Collins is dealing with a concussion, taking away quarterback C.J. Stroud's top option in the passing game.

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. Before you make any Texans vs. 49ers picks, make sure to check out what the SportsLine Project

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