Researchers have found in a new study that biological mesh offered no pain-reduction benefits and showed higher recurrence rates compared to synthetic mesh in laparoendoscopic hernia repair. The study was published in JAMA Surgery by Claudia S. and colleagues. Chronic postoperative pain and recurrence are still significant issues after inguinal hernia repair. Biological meshes, due to the resorbable nature, were brought in as a possibly safer and more comfortable solution to synthetic implants. The trial concluded that biologic meshes did not decrease postoperative pain and were significantly more likely to result in hernia recurrence than synthetic meshes.

The BIOLAP trial was a self-controlled, randomized, multicenter clinical trial involving between August 2017 and February 2021 in 2

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