A top-20 SEC matchup features the No. 18 Oklahoma Sooners (6-2) and the No. 14 Tennessee Volunteers (6-2) battling on Saturday afternoon. The Sooners have lost two of their last three games, falling 34-26 to Ole Miss in Week 9. Tennessee defeated Kentucky 56-34. on the road last week. Oklahoma leads the all-time series 3-2, but the Volunteers beat the Sooners 25-15 in 2024 in Tennessee coach Josh Heupel's return to his alma mater.

Kickoff from Neyland Stadium in Knoxville, Tenn., is at 7:30 p.m. ET. The Volunteers are 2.5-point favorites in the latest Oklahoma vs. Tennessee odds, while the over/under for total points scored is 55.5. Before making any Tennessee vs. Oklahoma picks, check out the college football predictions from the SportsLine Projection Model .

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