The Buffalo Bills host the Kansas City Chiefs at 4:25 p.m. Sunday at Highmark Stadium.

While the Bills will never admit it - because every regular-season game is just one of 17 in their minds - their annual measuring stick game is on tap.

Patrick Mahomes, Travis Kelce, Chris Jones and the rest of Andy Reid’s Kansas City Chiefs are coming to town for the latest renewal of what has become one of the NFL’s most anticipated games each season.

The Bills have owned the Chiefs in the regular season, having won the last four games, three of those in Kansas City. Last year, their victory in Orchard Park was one of the best games in the NFL. Watch Bills vs Chiefs live on Fubo

Bills vs. Chiefs odds, money line, over/under

Odds courtesy of BetMGM as of Friday, Oct. 31

Moneyline: Bil

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