Buffalo Bills quarterback Josh Allen (17) throws against the Carolina Panthers during the first half an NFL football game, Sunday, Oct. 26, 2025, in Charlotte, N.C. AP Gambling content 21+. The New York Post may receive an affiliate commission if you sign up through our links. Read our editorial standards for more information.

Few rivalries in football carry the electricity of Chiefs-Bills.

Kansas City heads to Orchard Park looking to reclaim its early-season dominance, while Buffalo shoots to extend its regular-season mastery over the Chiefs — winners of five of the last six non-playoff meetings.

Mahomes still owns the postseason narrative, but Josh Allen enters with confidence after a blowout win and a clean week of football.

The spread is narrow, the stakes are high as usual an

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