Multiple people were injured Tuesday after a UPS cargo plane crashed near Louisville Muhammad Ali International Airport (SDF) in Kentucky.

UPS Flight 2976 crashed at about 5:15 p.m. local time after departing from SDF, according to the Federal Aviation Administration (FAA).

The McDonnell Douglas MD-11 was headed to Daniel K. Inouye International Airport in Honolulu, FAA officials said.

The Louisville Metro Police Department confirmed its officers, along with multiple other agencies, were responding to the crash, which happened near the UPS Worldport.

Police said multiple people were injured. It is unclear if there were any fatalities.

"This is an active scene with fire and debris," police wrote in an X post. "Stay away."

The agency later issued an emergency shelter-in-place alert for

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