LOUISVILLE, Ky. (AP) — A large UPS cargo plane with three people aboard crashed and exploded Tuesday while taking off from an airport in Louisville, Kentucky, igniting a massive fire that left a thick plume of black smoke over the area.

The plane crashed about 5:15 p.m. as it was departing for Honolulu from Louisville’s Muhammad Ali International Airport, the Federal Aviation Administration said.

“We know that there are injuries. We don’t know yet about fatalities, but we’re asking all Kentuckians to pray for those that have been impacted,” Kentucky Gov. Andy Beshear told The Associated Press.

Mayor Craig Greenberg told WLKY-TV there could be about 280,000 gallons (1,059 kiloliters) of fuel on the plane, an “extreme reason for concern in so many different ways.”

UPS’s largest package h

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