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A plume of smoke rises from the site of a UPS cargo plane crash at Louisville Muhammad Ali International Airport on Tuesday, Nov. 4, 2025, in Louisville, Ky. (AP Photo/Jon Cherry)

LOUISVILLE, Ky. – At least seven people are dead after a UPS cargo plane crashed Tuesday while taking off from the Louisville airport, leaving a trail of flames just miles from the city’s downtown.

The plane crashed at about 5:15 p.m. after its left wing caught fire. The McDonnell Douglas MD-11 aircraft, made in 1991, was departing for Honolulu from UPS Worldport at Louisville Muhammad Ali International Airport.

Kentucky Gov. Andy Beshear said 11 others had “very significant” injuries.

The victims have not been identified publicly. Four of thos

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