KEY POINTS

A study links long-term melatonin use to increased heart failure risk and hospitalization.

The findings were presented at American Heart Association's Scientific Sessions 2025.

Researchers didn't prove causation between melatonin and health risks.

A new study raises safety concerns about long-term use of melatonin supplements by those with insomnia, noting that it appears to be associated with increased risk of heart failure. But while urging caution and suggesting more study, the authors also point out they have not shown that melatonin causes the adverse effects. Instead, they say caution is needed.

The findings are being presented as an abstract this weekend at the American Heart Association’s Scientific Sessions 2025 in New Orleans, according to a news release from th

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