A UPS cargo plane’s left wing caught fire and its engine fell off just before it crashed and exploded after takeoff in Kentucky.

The crash and fire Tuesday destroyed the plane and spread to nearby businesses in Louisville, Kentucky.

Authorities say at least nine people died and others are missing.

Three people were aboard when the plane crashed as it took off for Honolulu from UPS Worldport at Louisville’s Muhammad Ali International Airport. Video showed flames on the plane’s left wing and a trail of smoke.

J. Todd Inman, a member of the National Transportation Safety Board, spoke to reporters Wednesday.

Earlier Wednesday, first responders searched for more crash victims at the company’s global aviation hub in Kentucky. The subsequent inferno consumed the enormous aircraft and spread to nearby businesses, authorities said.