Federal investigators are working to determine what caused a UPS cargo plane to crash and erupt in a massive fireball Tuesday night in Louisville , killing at least nine people and leaving more than a dozen others unaccounted for.

Fiery UPS plane crash

What we know:

Authorities said the UPS MD-11 cargo jet went down around 5:15 p.m. as it departed Louisville Muhammad Ali International Airport’s UPS Worldport facility for Honolulu. Officials warned the death toll could rise.

Witness video showed flames on the plane’s left wing and a trail of smoke as it barreled down the runway. The National Transportation Safety Board said the aircraft’s left engine detached during the takeoff roll.

Officials said the plane was carrying more than 200,000 pounds of fuel for its long flight to Hawaii

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