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Cleveland Guardians pitchers Emmanuel Clase and Luis Ortiz have been indicted in relation to a scheme to rig bets on pitches thrown in MLB games ... TMZ has learned.

According to court documents, obtained by TMZ, their scheme allegedly worked like this ... the pitchers would agree in advance with their co-conspirators on what pitches they would throw in the games. Then, their co-conspirators would allegedly use that information to place hundreds of "fraudulent bets" on those pitches, which won them at least $400,000.

While Ortiz was arrested Sunday in Boston, Clase is not currently in custody. Ortiz is due to appear in federal court in Boston sometime on Monday, November 10. Getty

As we reported over the summer, Ortiz and Clase were placed on non-disciplinary paid leav

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