Grey’s Anatomy returns to core instincts in Season 22, Episode 5 — the hour titled “Sometimes I Feel Like a Motherless Child” — while setting up a perilous fall finale in “When I Crash” on Thursday, November 13, 2025 at 10 p.m. ET on ABC, with next‑day streaming on Hulu. The latest recap reveals how personal histories crash into hospital chaos, and why Jo Wilson’s delivery and Teddy Altman’s field rescue now look like life‑or‑death turns.

What happens in S22E5: “Sometimes I Feel Like a Motherless Child”

(Disney/Bahareh Ritter)

Meredith Grey’s voice‑over frames the theme: there’s “always one patient who can change everything for a doctor,” and this week that proves true for Simone, Benson Kwan, and Jo.

Simone’s exit shift is derailed when Lucas is late, so Richard Webber reassigns her

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