Daily Walks Potentially Sabotaged By Diabetes Drug, Study Says

Key Takeaways

The diabetes drug metformin mixes poorly with exercisePeople taking metformin got less health benefit from either high-intensity or low-intensity exerciseMetformin might interfere with the body’s cellular response to exercise

WEDNESDAY, Nov. 12, 2025 (HealthDay News) — A common diabetes drug could be sabotaging the health benefits that a patient might expect from a daily walk, a new study says.

Metformin appears to blunt improvements in blood pressure, fitness and blood sugar control that normally come from regular exercise, researchers report in The Journal of Clinical Endocrinology & Metabolism .

This complicates current guidelines that advise patients with high blood sugar to take metformin while engaging in exercise, researchers said. The reasoning: Two proven th