George Clooney Is Open to Reuniting With 'ER' Co-Star Noah Wyle on 'The Pitt'

George Clooney, the Academy Award-winning star in films like Ocean's Eleven, From Dusk till Dawn, and Burn After Reading, shot to stardom when he played Dr. Doug Ross on the NBC medical drama ER. It wasn't his big debut, as he had already appeared in plenty of TV shows and lesser-known movies, but ER was the one that put him on the map. The medical drama was also responsible for putting Noah Wyle in the spotlight, decades before his Emmy-winning performance in the 2025 HBO Max series The Pitt. Though the shows take place in different timelines and feature different characters, Clooney has addressed the possibility of reuniting with Wyle in the acclaimed drama. Will Dr. Ross enter the emergency room led by Dr. Robby? According to Clooney, there's a chance.