Plans to refocus Australia's leading science agency's priorities due to financial strain, resulting in hundreds of job losses, have been labelled "necessary" by a government minister, while scientist groups warn a lack of investment will stifle innovation.

The CSIRO has announced up to 350 full-time staff roles will be abolished as the agency embarks on a new research direction due to long-term financial sustainability challenges caused by funding not keeping pace with the rising costs of running a modern science agency.

The union representing the agency's workers and the peak body for scientists slammed the Albanese government for "devastating" cuts, which they said would hurt Australians and their futures.

After decades of stretching resources to maintain its programs and workforce, c

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