Week 12 of the 2025 NFL season arrives with the fantasy football playoffs looming. Running back has once again become the position where championships are won or lost. Week 11 delivered fireworks, led by Sean Tucker’s stunning eruption . That flipped matchups and waiver wires across the fantasy landscape. As always, though, the challenge now is separating true rest-of-season assets from one-week illusions.

Key insights

This week brings a lighter bye slate, with the Colts and Saints returning and only the Commanders, Dolphins, Broncos, and Chargers idle in Week 12. That keeps most of the top-tier fantasy football backs available. In fact, several matchups offering huge upside. As such, there’s plenty of potential for managers to swing their playoff push in the right direction.

Let’s

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