Inflammation may be responsible for driving earliest stages of lung cancer, suggests research

By creating high-resolution cellular and molecular visual maps of lung cancer before and during development, researchers at The University of Texas MD Anderson Cancer Center have discovered that the earliest stages of lung cancer may be driven by inflammation , suggesting that targeting proinflammatory pathways could be an early intervention approach.

The study, published today in Cancer Cell , generated spatial transcriptomic maps in precancerous and more advanced stages of lung cancer to provide a deeper understanding of early lung cancer development. The research was led by Humam Kadara, Ph.D., professor of Translational Molecular Pathology, and Linghua Wang, M.D., Ph.D., professor of Genomic Medicine, associate member of the James P. Allison Institute™ and focus area co-lead wit