No team has a worst NFL spread record than Washington, but with it on a bye, you'll have to pick on other teams with your Week 12 NFL bets. Tennessee could be that squad as it has just one more ATS victory than the Commanders, and the Titans take on a Seattle team which has covered a league-high eight times. A thorough Week 12 NFL betting guide will look at trends like these, while also taking into account recent performances, injuries and more to allow you to be fully informed before making any NFL predictions.

Seahawks vs. Titans (+13.5), along with Steelers vs. Bears (-2.5) and Jaguars vs. Cardinals (+2.5), are the lone cross-conference games this week. Apart from making Week 12 NFL picks against the spread for them, the likes of Jaxon Smith-Njigba, D.K. Metcalf, Caleb Williams and Tra

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