Thunder Dan's favorite RB matchups to exploit for Week 12 of 2025 - DFS running backs to target on DraftKings and FanDuel. These RB matchups are GPP and cash game opportunities.

This is setting up for a really fantastic week of NFL DFS, and in weeks like this one, where we don't have someone like CMC in a smash spot soaking up a bunch of rostership, those who are willing to dig in a little deeper on matchups should be rewarded.

My player pool for tournaments isn't limited to just this list of backs; however, they are almost always my most highly-rostered players. That will likely be the case this week, too, except for Emanuel Wilson , who becomes a must-start for cash games if Josh Jacobs ends up sitting out.

However, these are also running backs you should smash into your season-lo

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