The No. 16 USC Trojans (8-2, 6-1 Big Ten) and No. 5 Oregon Ducks (9-1, 6-1) meet Saturday at Autzen Stadium in Eugene, Oregon. Kickoff is scheduled for 3:30 p.m. ET (CBS). Let's analyze BetMGM Sportsbook's NCAA football odds around the USC vs. Oregon odds and make our expert college football picks and predictions for the best bets.

USC leads the all-time series 38-23-2, but Oregon has won the past 3 meetings since Nov. 11, 2023. This is the first-ever meeting between the teams as members of the Big Ten.

The Trojans topped Iowa 26-21 last Saturday, but the Hawkeyes covered as 6.5-point underdogs as the Under (48.5) cashed. QB Jayden Maiava threw for 254 yards, 1 TD and 11 rushing yards, while hooking up with WR Makai Lemon 10 times for 153 yards and a score. RB Bryan Ja

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