Oct 11, 2025; Champaign, Illinois, USA; Illinois Fighting Illini head coach Bret Bielema leads his team in the Illini Walk before an NCAA game against the Ohio State Buckeyes at Memorial Stadium. Mandatory Credit: Ron Johnson-Imagn Images

Late season in the Big Ten means cold weather, physical play, and toughness in running the ball. Week 13 brings a matchup of one team trying to take that identity on the road.

The Illinois Fighting Illini (7-3, 4-3 Big Ten) are freshly ranked in the College Football Playoff rankings and are aiming for win No. 8 with a road trip to take on the Wisconsin Badgers from Camp Randall Stadium in Madison, Wisconsin.

If you are looking for some betting advice for the matchup, we've got you covered. Here are the latest odds for the game, courtesy of BetMGM.

Illinois vs. Wisconsin game odds:

All college football odds via BetMGM

  • Spread: Illinois -7.5 (-115), Wisconsin +7.5 (-105)
  • Money Line: Illinois -350, Wisconsin +270
  • Over-Under: Over 40.5 (-115), Under 40.5 (-105)

Illinois vs. Wisconsin prediction, pick:

The Illini have new life injected into them after finally getting ranked in the College Football Playoff rankings. While a playoff trip is a long shot, the Illini have a real chance at an upper-echelon bowl game, which this program embraces under head coach Bret Bielema.

Wisconsin, on the other hand, can't catch a break. The Badgers have played, in a row: Michigan, Iowa, Ohio State, Oregon, Washington, and Indiana. While they did upset Washington, they didn't really even compete otherwise.

This is another tough matchup for Wisconsin's offense, which has struggled all year, against an Illinois defense that isn't great, but can slow down the run game and make the Badgers have to drop back and throw it, something they haven't proven successful in yet.

Prediction: Illinois 27, Wisconsin 10

Best Bet: Illinois -7.5

Illinois vs. Wisconsin channel, start time, streaming:

Time: 7:30 p.m. ET

TV Channel: Big Ten Network

Live Stream: Big Ten Network App

Watch Illinois vs. Wisconsin on FuboTV (Free Trial)

Get more betting analysis and predictions at Sportsbook Wire.

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This article originally appeared on College Sports Wire: Illinois vs. Wisconsin: College Football Betting Odds, Prediction

Reporting by Riley Donald, College Sports Wire / College Sports Wire

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