Week 12 has arrived for NFL DFS players, and there are three matchups on the Sunday 'main slate' that feature an over/under of 50 points or higher. Lions vs. Giants, Colts vs. Chiefs and Patriots vs. Bengals will all be potential sources of major offense. NFL DFS lineups won't feature Ja'Marr Chase (suspension), Joe Burrow (toe) or Jaxson Dart (concussion) this week, but big names like Amon-Ra St. Brown, Drake Maye and Patrick Mahomes are all in play.

Which NFL DFS picks from those matchups should you target, and are there players from potentially lower-scoring games like Seahawks vs. Titans or Raiders vs. Browns who should factor into your NFL DFS strategy? Before making any NFL DFS picks for Week 12, be sure to check out the NFL DFS advice, strategy, and stacks from SportsLine daily Fa

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