On a night of changes, blunders and a glorious individual goal by 18-year-old Estevão, defensive lapses cost Manchester City and Barcelona dearly as both teams slumped to notable losses in the Champions League on Tuesday.

In Pep Guardiola's 100th Champions League game as City coach, his team struggled to cope with Bayer Leverkusen's quick transitions in a 2-0 defeat, while Barcelona had an own goal and a red card in its 3-0 loss at Chelsea.

Guardiola made 10 changes to his starting lineup following Saturday’s loss to Newcastle in the Premier League, with Erling Haaland among those on the bench, but it didn’t have the desired effect.

Alejandro Grimaldo fired home Leverkusen’s first goal with a low shot into the far corner in the 23rd and Patrik Schick headed in a second in the 54th.

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