Oregon Ducks quarterback Dante Moore (5) throws a pass against the Southern California Trojans during the second half at Autzen Stadium in Eugene, Oregon.

The No. 5 Oregon Ducks (10-1, 7-1 Big Ten) and Washington Huskies (8-3, 5-3) meet Saturday at Husky Stadium in Seattle, Washington. Kickoff is scheduled for 3:30 p.m. ET (CBS). Let's analyze BetMGM Sportsbook's NCAA football odds around the Oregon vs. Washington odds and make our expert college football picks and predictions for the best bets.

Washington leads the all-time series 63-49-5, although Oregon won 49-21 as a 17-point favorite in Eugene last season on Nov. 30, 2024, as the Over (50) hit in the first meeting each as Big Ten members.

Oregon topped USC 42-27 last Saturday in another Pac-12 reunion game, covering as 10.5-point favorite as the Over (59.5) cashed. QB Dante Moore passed for 257 yards, 2 TDs and 1 INT, while RB Noah Whittington rushed for 104 yards and a TD, and RB Jordon Davison had 50 rushing yards and a score. TE Kenyon Sadiq had 6 grabs for 72 yards and 2 TDs.

Washington belted UCLA 48-14 as an 11.5-point favorite as the Over (50.5) cashed last week. QB Demond Williams Jr. passed for 213 yards, 2 TDs and 1 INT, while running for 56 yards and 2 scores. Since a 13-10 upset loss at Wisconsin in the wind and rain, the Huskies have averaged 48.5 PPG in the past 2 games while allowing 13.5 PPG, going 2-0 against the spread (ATS) with 2 Over results.

Washington has won 3 of the past 4 games. It has gone 3-1 ATS and 3-1 to the Over in the same 4-game span. Oregon has won 5 in a row, while going just 3-3 ATS in the past 6 games, with the Over holding a slight 3-2 edge in the past 5 outings.

The weather forecast is favorable for Seattle, a rarity at this time of year. It will be cloudy and 45 degrees with a 20 percent chance of precipitation with winds at 4-6 mph.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Oregon at Washington odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:15 a.m. ET.

  • Moneyline (ML): Oregon -275 (bet $275 to win $100) | Washington +225 (bet $100 to win $225)
  • Against the spread: Oregon -7 (-110) | Washington +7 (-110)
  • Over/Under (O/U): 51.5 (O: -110 | U: -110)

Oregon at Washington picks and predictions

Prediction

Oregon 31, Washington 27

Moneyline

Oregon (-275) will cost you nearly 3 times your potential return, and that's quite a bit risky in this border war rivalry. The Ducks are trying to keep their College Football Playoff hopes alive, while the Huskies are trying to spoil those plans for their rivals, while also improving their bowl situation substantially. It should be a nip and tuck affair.

PASS.

Against the spread

WASHINGTON +7 (-110) has a talented and dangerous offense, led by the dual threat Williams Jr. It wouldn't be stunning in the least to see the Huskies pull the upset.

Oregon's offense struggled in a pair of narrow victories against Iowa and Wisconsin, but in the past 2 games, it has looked more like a CFP-worthy team, posting 42 points in back-to-back games. If it makes it to the playoffs with a win over the Huskies, it will have earned that spot.

Over/Under

OVER 51.5 (-110) might be the best play on the board in this Pac-12 reunion.

The Ducks have gotten untracked with 42 points in each of the past 2 games, including a clash with USC last week. It has scored 30 or more points in 8 of 11 games so far this season, going Over in 2 of the past 3 road outings.

The Huskies have cashed high in the past 2 games, averaging 48.5 PPG in the past 2 games, while going for 38 or more points in 4 of the past 6 outings.

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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This article originally appeared on Sportsbook Wire: Oregon Ducks at Washington Huskies odds, picks and predictions

Reporting by Daniel Dobish, Sportsbook Wire / Sportsbook Wire

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